Internal Carotid Artery
The main artery of the anterior circulation, ascending from the neck through the skull base to supply most of the cerebral hemisphere on its side.
On MRI: On the sagittal TOF MIP it is the large bright vessel sweeping up through the carotid canal and cavernous segment, making its characteristic S-shaped carotid siphon before branching into the anterior and middle cerebral arteries.
Common pathology: Atherosclerotic stenosis, dissection, and aneurysms at the cavernous and supraclinoid segments; occlusion threatens the entire anterior circulation territory.